Recombinant Proteins

Human Nerve Growth Factor (hNGF) is a critical neurotrophin responsible for the growth, maintenance, and survival of target neurons. Because hNGF relies on a complex network of disulfide bonds for its biological activity, our recombinant version is uniquely fused to DsbC (a bacterial disulfide isomerase). Expressed in E. coli, this DsbC tag promotes correct folding and vastly improves solubility, delivering a highly active and stable protein for your assays. The DsbC tagged hNGF has been demonstrated to exhibit functonal activity in cell based assays

Human Tropomyosin Receptor Kinase A Domain 5 (hTrkAd5)
Tropomyosin Receptor Kinase A (TrkA) is the high-affinity catalytic receptor for NGF, playing a vital role in neural development and pain signal transmission. Domain 5 (TrkAd5) is the specific extracellular region responsible for NGF binding. TrkAd5 is recombinantly expressed in E. coli, and demonstrated to be functional in cell based assays. 

Canine Tropomyosin Receptor Kinase A Domain 5 (cTrkAd5)
Designed specifically to support veterinary research and comparative models, this is the canine ortholog of the primary NGF-binding domain. As anti-NGF monoclonal antibodies become a leading treatment for canine osteoarthritis and chronic pain, our E. coli-expressed cTrkAd5 provides researchers with a reliable, highly purified target for binding assays.

Mini-Spidroin
Spidroins are the core structural proteins that give spider silk its legendary tensile strength, toughness, and elasticity. Our Mini-Spidroin is a truncated, highly stable recombinant construct designed to capture the unique mechanical properties of natural spider dragline silk. Expressed efficiently in E. coli, it serves as a powerful building block for researchers developing advanced biomaterials.